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A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels

Tumor initiation, development, and relapse may be closely associated with cancer stem cells (CSCs). The complicated mechanisms underlying the maintenance of CSCs are keeping in illustration. Long noncoding RNAs (lncRNAs), due to their multifunction in various biological processes, have been indicate...

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Detalles Bibliográficos
Autores principales: Wen, Siyang, Qin, Yilu, Wang, Rui, Yang, Liping, Zeng, Huan, Zhu, Pengpeng, Li, Qiao, Qiu, Yuxiang, Chen, Shanchun, Liu, Yongcan, Hou, Yixuan, Tang, Xi, Liu, Manran, Tu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088435/
https://www.ncbi.nlm.nih.gov/pubmed/33934099
http://dx.doi.org/10.1038/s41419-021-03708-6