Cargando…

Intermedin(1-53) attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to be a key mechanism of macrophage apoptosis. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Zhang, Ya-Rong, Liu, Shi-Meng, Yu, Yan-Rong, Jia, Mo-Zhi, Tang, Chao-Shu, Qi, Yong-Fen, Lu, Wei-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088440/
https://www.ncbi.nlm.nih.gov/pubmed/33934111
http://dx.doi.org/10.1038/s41419-021-03712-w