PINK1‐mediated mitophagy maintains pluripotency through optineurin

OBJECTIVES: Dysfunction of autophagy results in accumulation of depolarized mitochondria and breakdown of self‐renewal and pluripotency in ESCs. However, the regulators that control how mitochondria are degraded by autophagy for pluripotency regulation remains largely unknown. This study aims to dis...

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Detalles Bibliográficos
Autores principales: Wang, Chaoqun, Liu, Kun, Cao, Jiani, Wang, Liang, Zhao, Qian, Li, Zheng, Zhang, Honghai, Chen, Quan, Zhao, Tongbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088463/
https://www.ncbi.nlm.nih.gov/pubmed/33931895
http://dx.doi.org/10.1111/cpr.13034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088463/
https://www.ncbi.nlm.nih.gov/pubmed/33931895
http://dx.doi.org/10.1111/cpr.13034

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