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Periodontitis‐compromised dental pulp stem cells secrete extracellular vesicles carrying miRNA‐378a promote local angiogenesis by targeting Sufu to activate the Hedgehog/Gli1 signalling

OBJECTIVES: Previously, our investigations demonstrated robust pro‐angiogenic potentials of extracellular vesicles secreted by periodontitis‐compromised dental pulp stem cells (P‐EVs) when compared to those from healthy DPSCs (H‐EVs), but the underlying mechanism remains unknown. MATERIALS AND METHO...

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Detalles Bibliográficos
Autores principales: Zhou, Huan, Li, Xuan, Wu, Rui‐Xin, He, Xiao‐Tao, An, Ying, Xu, Xin‐Yue, Sun, Hai‐Hua, Wu, Li‐An, Chen, Fa‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088471/
https://www.ncbi.nlm.nih.gov/pubmed/33759282
http://dx.doi.org/10.1111/cpr.13026