Overview on population screening for carriers with germline mutations in mismatch repair (MMR) genes in China

DNA mismatch repair (MMR) genes play an important role in maintaining genome stability. Germline mutations in MMR genes disrupt the mismatch repair function and cause genome instability. Carriers with MMR germline mutations are more likely to have MMR deficiency and microsatellite instability (MSI)...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Chen, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088635/
https://www.ncbi.nlm.nih.gov/pubmed/33933134
http://dx.doi.org/10.1186/s13053-021-00182-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088635/
https://www.ncbi.nlm.nih.gov/pubmed/33933134
http://dx.doi.org/10.1186/s13053-021-00182-1

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