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LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis

BACKGROUND: Leucine rich repeat containing 4 (LRRC4), also known as netrin-G ligand-2 (NGL-2), belongs to the superfamily of LRR proteins and serves as a receptor for netrin-G2. LRRC4 regulates the formation of excitatory synapses and promotes axon differentiation. Mutations in LRRC4 occur in Autism...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Li, Di, Zeng, Qiuming, Feng, Jianbo, Fu, Haijuan, Luo, Zhaohui, Xiao, Bo, Yang, Huan, Wu, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088686/
https://www.ncbi.nlm.nih.gov/pubmed/33932995
http://dx.doi.org/10.1186/s10020-021-00304-4