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Chimeric antigen receptor natural killer (CAR-NK) cell design and engineering for cancer therapy

Due to their efficient recognition and lysis of malignant cells, natural killer (NK) cells are considered as specialized immune cells that can be genetically modified to obtain capable effector cells for adoptive cellular treatment of cancer patients. However, biological and technical hurdles relate...

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Detalles Bibliográficos
Autores principales: Gong, Ying, Klein Wolterink, Roel G. J., Wang, Jianxiang, Bos, Gerard M. J., Germeraad, Wilfred T. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088725/
https://www.ncbi.nlm.nih.gov/pubmed/33933160
http://dx.doi.org/10.1186/s13045-021-01083-5