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Chimeric antigen receptor natural killer (CAR-NK) cell design and engineering for cancer therapy
Due to their efficient recognition and lysis of malignant cells, natural killer (NK) cells are considered as specialized immune cells that can be genetically modified to obtain capable effector cells for adoptive cellular treatment of cancer patients. However, biological and technical hurdles relate...
Autores principales: | Gong, Ying, Klein Wolterink, Roel G. J., Wang, Jianxiang, Bos, Gerard M. J., Germeraad, Wilfred T. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088725/ https://www.ncbi.nlm.nih.gov/pubmed/33933160 http://dx.doi.org/10.1186/s13045-021-01083-5 |
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