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Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases
T follicular helper cells participate in stimulating germinal center (GC) formation and supporting B cell differentiation and autoantibody production. However, T follicular regulatory (Tfr) cells suppress B cell activation. Since changes in the number and functions of Tfr cells lead to dysregulated...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088831/ https://www.ncbi.nlm.nih.gov/pubmed/33934711 http://dx.doi.org/10.1186/s41232-021-00164-9 |