Comparison of N-linked glycosylation on hemagglutinins derived from chicken embryos and MDCK cells: a case of the production of a trivalent seasonal influenza vaccine

ABSTRACT: N-linked glycosylation plays critical roles in folding, receptor binding, and immunomodulating of hemagglutinin (HA), the main antigen in influenza vaccines. Chicken embryos are the predominant production host for influenza vaccines, but Madin-Darby canine kidney (MDCK) cells have emerged...

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Detalles Bibliográficos
Autores principales: Li, Jingqi, Liu, Sixu, Gao, Yanlin, Tian, Shuaishuai, Yang, Yu, Ma, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088833/
https://www.ncbi.nlm.nih.gov/pubmed/33937925
http://dx.doi.org/10.1007/s00253-021-11247-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088833/
https://www.ncbi.nlm.nih.gov/pubmed/33937925
http://dx.doi.org/10.1007/s00253-021-11247-5

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