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Comparison of N-linked glycosylation on hemagglutinins derived from chicken embryos and MDCK cells: a case of the production of a trivalent seasonal influenza vaccine
ABSTRACT: N-linked glycosylation plays critical roles in folding, receptor binding, and immunomodulating of hemagglutinin (HA), the main antigen in influenza vaccines. Chicken embryos are the predominant production host for influenza vaccines, but Madin-Darby canine kidney (MDCK) cells have emerged...
Autores principales: | Li, Jingqi, Liu, Sixu, Gao, Yanlin, Tian, Shuaishuai, Yang, Yu, Ma, Ningning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088833/ https://www.ncbi.nlm.nih.gov/pubmed/33937925 http://dx.doi.org/10.1007/s00253-021-11247-5 |
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