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Epigenetics of Indolent Lymphoma and How It Drives Novel Therapeutic Approaches—Focus on EZH2-Targeted Drugs

PURPOSE OF REVIEW: Epigenetic modifier gene mutations are common in patients with follicular lymphoma. Here we review the pathogenesis of these mutations and how they are targeted by epigenetic drugs including EZH2 inhibitors in both mutated and wild-type disease. RECENT FINDINGS: The use of EZH2 in...

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Detalles Bibliográficos
Autores principales: Longley, Jemma, Johnson, Peter W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088902/
https://www.ncbi.nlm.nih.gov/pubmed/33937922
http://dx.doi.org/10.1007/s11912-021-01076-0