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N‐glycosylated GPNMB ligand independently activates mutated EGFR signaling and promotes metastasis in NSCLC

Lung cancer is the leading cause of cancer‐related death worldwide. As well as the identified role of epidermal growth factor receptor (EGFR), its association with driver mutations has improved the therapeutics for patients with lung cancer harboring EGFR mutations. These patients usually display sh...

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Detalles Bibliográficos
Autores principales: Han, Chia‐Li, Chen, Xuan‐Ren, Lan, Albert, Hsu, Yuan‐Ling, Wu, Pei‐Shan, Hung, Pei‐Fang, Hung, Chung‐Lieh, Pan, Szu‐Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088973/
https://www.ncbi.nlm.nih.gov/pubmed/33706413
http://dx.doi.org/10.1111/cas.14872