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Forsythoside A Alleviates High Glucose-Induced Oxidative Stress and Inflammation in Podocytes by Inactivating MAPK Signaling via MMP12 Inhibition

BACKGROUND: Podocyte injury serves an important role during the progression of diabetic nephropathy (DN). The aim of this study was to investigate the effects of forsythoside A (FA) on high glucose (HG)-induced podocyte injury and to identify the possible mechanisms. METHODS: MPC-5 podocytes were cu...

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Detalles Bibliográficos
Autores principales: Quan, Xiaohong, Liu, Huihui, Ye, Dongmei, Ding, Xinling, Su, Xiulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089089/
https://www.ncbi.nlm.nih.gov/pubmed/33953587
http://dx.doi.org/10.2147/DMSO.S305092