Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice

BACKGROUND: Prolonged exposure to high oxygen concentrations in premature infants, although lifesaving, can induce lung oxidative stress and increase the risk of developing BPD, a form of chronic lung disease. The lung alveolar epithelium is damaged by sustained hyperoxia, causing oxidative stress a...

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Detalles Bibliográficos
Autores principales: Garcia, David, Carr, Jennifer F., Chan, Felix, Peterson, Abigail L., Ellis, Kimberlyn A., Scaffa, Alejandro, Ghio, Andrew J., Yao, Hongwei, Dennery, Phyllis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089115/
https://www.ncbi.nlm.nih.gov/pubmed/33144707
http://dx.doi.org/10.1038/s41390-020-01224-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089115/
https://www.ncbi.nlm.nih.gov/pubmed/33144707
http://dx.doi.org/10.1038/s41390-020-01224-5

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