Cargando…
Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice
BACKGROUND: Prolonged exposure to high oxygen concentrations in premature infants, although lifesaving, can induce lung oxidative stress and increase the risk of developing BPD, a form of chronic lung disease. The lung alveolar epithelium is damaged by sustained hyperoxia, causing oxidative stress a...
Autores principales: | Garcia, David, Carr, Jennifer F., Chan, Felix, Peterson, Abigail L., Ellis, Kimberlyn A., Scaffa, Alejandro, Ghio, Andrew J., Yao, Hongwei, Dennery, Phyllis A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089115/ https://www.ncbi.nlm.nih.gov/pubmed/33144707 http://dx.doi.org/10.1038/s41390-020-01224-5 |
Ejemplares similares
-
Hyperoxia causes senescence and increases glycolysis in cultured lung epithelial cells
por: Scaffa, Alejandro M., et al.
Publicado: (2021) -
The pentose phosphate pathway mediates hyperoxia-induced lung vascular dysgenesis and alveolar simplification in neonates
por: Gong, Jiannan, et al.
Publicado: (2021) -
Heme Oxygenase-1 Supports Mitochondrial Energy Production and Electron Transport Chain Activity in Cultured Lung Epithelial Cells
por: Carr, Jennifer F., et al.
Publicado: (2020) -
Heme Oxygenase 1 and 2 Differentially Regulate Glucose Metabolism and Adipose Tissue Mitochondrial Respiration: Implications for Metabolic Dysregulation
por: Yao, Hongwei, et al.
Publicado: (2020) -
Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury
por: Chang, Jason L., et al.
Publicado: (2022)