Cargando…

Triple Negative Breast Cancer is Dependent on the Lysosomal Cholesterol Transporter NPC1

Background: Triple Negative Breast Cancer (TNBC) is an aggressive subtype of breast cancer (BC) with peak rate of metastasis within the first few years post diagnosis and few targeted therapies. Normal epithelial cells and estrogen receptor alpha (ER) positive BC express the microRNA-200c (miR-200c)...

Descripción completa

Detalles Bibliográficos
Autor principal: O’Neill, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089138/
http://dx.doi.org/10.1210/jendso/bvab048.2116