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Intracellular Cholesterol Metabolism in Aldosterone-Producing Adenoma.~A Possible Association With Cellular Morphometry and Genotype~

Introduction: Primary aldosteronism (PA) is the most common cause of secondary hypertension. More than 70% of APAs have been reported to have KCNJ5 somatic mutation in Asian countiries. Patients with KCNJ5 mutated APAs generally harbor high plasma aldosterone concentration (PAC), and are mainly comp...

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Detalles Bibliográficos
Autores principales: Harashima, Shogo, Yamazaki, Yuto, Ono, Yoshikiyo, Omata, Kei, Tezuka, Yuta, Morimoto, Ryo, Nakamura, Yasuhiro, Satoh, Fumitoshi, Suzuki, Hiroyoshi, Sasano, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089227/
http://dx.doi.org/10.1210/jendso/bvab048.140