Inhibition of ALDH1A1 Activity in Cisplatin-Resistant Ovarian Cancer Cells Alters Their Cancer Stemness, Cell Cycle Profile and Mitochondrial Respiration Rate

Introduction: Ovarian cancer is one of the leading cause of morbidity and death among women, with a five-year relative survival rate of only 30% in patients diagnosed with distant metastasis. The ovarian cancer cells initially respond to first-line platinum drug cisplatin [cis-diamminedichloroplatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramachandran, Ilangovan, Ramadoss, Sivakumar, Sen, Suvajit, Karuppaiyah, Selvendiran, Kumaran, R Ileng, Chaudhuri, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089254/
http://dx.doi.org/10.1210/jendso/bvab048.2094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089254/
http://dx.doi.org/10.1210/jendso/bvab048.2094

Ejemplares similares