Antiandrogens Target TMPRSS2 and Reduce SARS-CoV-2 Virus Entry in Lung Cells

The SARS-CoV-2 coronavirus is the cause of the COVID-19 pandemic. Entry of the virus into host cells, most destructively lung cells, requires two host cell surface proteins, ACE2 and TMPRSS2, downregulation of which is thus a potential therapeutic approach for COVID-19. Both of these cell surface pr...

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Detalles Bibliográficos
Autores principales: Leach, Damien A, Andrea, Mohr, Zwacka, Ralf, Giottis, Stathis, Yates, Laura, Lloyd, Clare, Brooke, Greg N, Bevan, Charlotte Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Adipose Tissue, Appetite, and Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089274/
http://dx.doi.org/10.1210/jendso/bvab048.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089274/
http://dx.doi.org/10.1210/jendso/bvab048.123

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