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Osteoblast-Induced Prostate Cancer Cell Migration and Invasion Is Mediated Through TGF-β1/SMAD2 Signal Pathway and Blocked by 17α-Estradiol

Prostate cancer (PCa) is curable if it is diagnosed and treated in localized and regional stage. However, PCa outcome is poor once it has distant metastasis. Approximately 70% to 100% of PCa deaths have bone metastasis, which may be associated with a specific bone microenvironment. In this study, we...

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Detalles Bibliográficos
Autores principales: Shi, Jian, Zhao, Lian, Duncan, Brittany, Su, Jie, Manzo, Jale, Liu, He, Zhu, Yuan-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089309/
http://dx.doi.org/10.1210/jendso/bvab048.2105