Taking Advantage of the TGFB1 Biology in Differentiated Thyroid Cancer to Stimulate Sodium Iodide Symporter (NIS)-Mediated Iodide Uptake in Engineered Mesenchymal Stem Cells

The sodium iodide symporter (NIS) mediates the active transport of iodide into thyroid follicular cells, providing the basis for the use of radioiodide for diagnostic imaging and therapy of differentiated thyroid cancer and also non-thyroidal tumors after tumor-selective NIS gene transfer. Based on...

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Detalles Bibliográficos
Autores principales: Han, Yang, Koehler, Viktoria F, Schwenk, Nathalie, Schmohl, Kathrin A, Spellerberg, Rebekka, Kitzberger, Carolin, Nelson, Peter J, Spitzweg, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089325/
http://dx.doi.org/10.1210/jendso/bvab048.2114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089325/
http://dx.doi.org/10.1210/jendso/bvab048.2114

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