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Taking Advantage of the TGFB1 Biology in Differentiated Thyroid Cancer to Stimulate Sodium Iodide Symporter (NIS)-Mediated Iodide Uptake in Engineered Mesenchymal Stem Cells
The sodium iodide symporter (NIS) mediates the active transport of iodide into thyroid follicular cells, providing the basis for the use of radioiodide for diagnostic imaging and therapy of differentiated thyroid cancer and also non-thyroidal tumors after tumor-selective NIS gene transfer. Based on...
Autores principales: | Han, Yang, Koehler, Viktoria F, Schwenk, Nathalie, Schmohl, Kathrin A, Spellerberg, Rebekka, Kitzberger, Carolin, Nelson, Peter J, Spitzweg, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089325/ http://dx.doi.org/10.1210/jendso/bvab048.2114 |
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