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Neoepitopes in Type 1 Diabetes: Etiological Insights, Biomarkers and Therapeutic Targets

The mechanisms underlying type 1 diabetes (T1D) pathogenesis remain largely unknown. While autoantibodies to pancreatic beta-cell antigens are often the first biological response and thereby a useful biomarker for identifying individuals in early stages of T1D, their role in T1D pathogenesis is not...

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Detalles Bibliográficos
Autores principales: Rodriguez-Calvo, Teresa, Johnson, James D., Overbergh, Lut, Dunne, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089389/
https://www.ncbi.nlm.nih.gov/pubmed/33953728
http://dx.doi.org/10.3389/fimmu.2021.667989