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The 5-Phosphatase SHIP2 Promotes Neutrophil Chemotaxis and Recruitment

Neutrophils, the most abundant circulating leukocytes in humans have key roles in host defense and in the inflammatory response. Agonist-activated phosphoinositide 3-kinases (PI3Ks) are important regulators of many facets of neutrophil biology. PIP3 is subject to dephosphorylation by several 5’ phos...

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Detalles Bibliográficos
Autores principales: Michael, Melina, McCormick, Barry, Anderson, Karen E., Karmakar, Utsa, Vermeren, Matthieu, Schurmans, Stéphane, Amour, Augustin, Vermeren, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089392/
https://www.ncbi.nlm.nih.gov/pubmed/33953730
http://dx.doi.org/10.3389/fimmu.2021.671756