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miR-4456/CCL3/CCR5 Pathway in the Pathogenesis of Tight Junction Impairment in Chronic Obstructive Pulmonary Disease

Background: Cigarette smoke exposure (CSE) is a major cause of chronic obstructive pulmonary disease (COPD). The smoke disrupts cell-cell adhesion by inducing epithelial barrier damage to the tight junction (TJ) proteins. Even though the inflammatory mechanism of chemokine (C-C motif) ligand 3 (CCL3...

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Detalles Bibliográficos
Autores principales: Yu, Weiwei, Ye, Ting, Ding, Jie, Huang, Yi, Peng, Yang, Xia, Qin, Cuntai, Zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089484/
https://www.ncbi.nlm.nih.gov/pubmed/33953665
http://dx.doi.org/10.3389/fphar.2021.551839