Hepatic GH Receptor Signaling Directly Suppresses Hepatic Steatosis and De Novo Lipogenesis, Independent of Changes in Plasma IGF1 and Insulin

A reduction in GH, as well as IGF1, is associated with non-alcoholic fatty liver disease (NAFLD). However, the relative contribution of changes in circulating GH and IGF1, to hepatic triglyceride accumulation (steatosis), remains to be clearly defined. To study the direct actions of GH on hepatocyte...

Descripción completa

Detalles Bibliográficos
Autores principales: Vazquez Borrego, Maria del Carmen, Moreno, Mercedes del Rio, Sarmento-Cabral, Andre, Mahmood, Mariyah, Subbaiah, Papasani V, Yakar, Shoshana, Cordoba-Chacon, Jose, Puchowicz, Michelle, Kineman, Rhonda D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Adipose Tissue, Appetite, and Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089597/
http://dx.doi.org/10.1210/jendso/bvab048.095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089597/
http://dx.doi.org/10.1210/jendso/bvab048.095

Ejemplares similares