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Assessment of Estradiol-Induced Gonadotropin Surge Generation: Preliminary Results From a Protocol of Graded Transdermal Estradiol Dosing

In normally-cycling women, high midcycle estradiol (E2) concentrations (> 200-300 pg/ml) derived from the dominant follicle trigger an approximately 10-fold increase in LH and 4-fold increase in FSH levels—the gonadotropin surge—over about 48 hours. In prenatally-androgenized female rats and shee...

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Detalles Bibliográficos
Autores principales: McCartney, Christopher R, Gilrain, Melissa, Lundgren, Jessica A, Kim, Su Hee, Solorzano, Christine Michele Burt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089709/
http://dx.doi.org/10.1210/jendso/bvab048.1484