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Hypothalamic Glucagon Receptors Regulate Feeding in Mice

Glucagon is an essential regulator of glucose and lipid metabolism. We have reported that chronic glucagon receptor (GCGR) activation with the highly selective, long-acting GCGR-agonist, IUB288, promotes weight-loss by stimulating energy expenditure and suppressing food intake in diet-induced obese...

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Detalles Bibliográficos
Autores principales: Cunningham, Stephen E, Nason, Shelly R, Presedo, Natalie, Kim, Teayoun, Antipenko, Jessica, DiMarchi, Richard D, Habegger, Kirk M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089716/
http://dx.doi.org/10.1210/jendso/bvab048.097