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LBD Dimerization of the Androgen Receptor but Not N/C Interaction Is Crucial for Normal Male Development in Mice
The androgen receptor (AR) is a nuclear receptor with a main role in the development and maintenance of the male phenotype. To execute its role as transcription factor, the AR forms homodimers. Three dimerization modes have been described for the AR: one via the DNA binding domain, a second via the...
Autores principales: | El Kharraz, Sarah, Helsen, Christine, Dubois, Vanessa, Libert, Claude, Poutanen, Matti, Claessens, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089729/ http://dx.doi.org/10.1210/jendso/bvab048.1675 |
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