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Paternal Obesity and SGLT2 Inhibition Alter Expression of Placental Regulatory Genes

We previously demonstrated that paternal obesity is associated with offspring metabolic risk during later life, and that paternal SGLT2i treatment improves offspring metabolic phenotypes. Since the placenta is a key determinant of prenatal growth and development, we hypothesized the placenta could m...

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Detalles Bibliográficos
Autores principales: Su, Lei, Osataphan, Soravis, Desmond, Jessica, Fang, Rui, Chimene-Weiss, Jeremy, Zhou, Liyuan, Efthymiou, Vissarion, Dreyfuss, Jonathan, Pan, Hui, Patti, Mary-Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089822/
http://dx.doi.org/10.1210/jendso/bvab048.1530