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Paternal Obesity and SGLT2 Inhibition Alter Expression of Placental Regulatory Genes
We previously demonstrated that paternal obesity is associated with offspring metabolic risk during later life, and that paternal SGLT2i treatment improves offspring metabolic phenotypes. Since the placenta is a key determinant of prenatal growth and development, we hypothesized the placenta could m...
Autores principales: | Su, Lei, Osataphan, Soravis, Desmond, Jessica, Fang, Rui, Chimene-Weiss, Jeremy, Zhou, Liyuan, Efthymiou, Vissarion, Dreyfuss, Jonathan, Pan, Hui, Patti, Mary-Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089822/ http://dx.doi.org/10.1210/jendso/bvab048.1530 |
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