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Tgm2-p62-p53 Complex May Function as an Autophagic Regulator Through Fyn and Involve in Diabetic Kidney Disease

Diabetic kidney disease (DKD) is one of the major diabetic complications and the leading cause of the end stage renal disease. Recently autophagy was shown to regulate DKD. Previously we reported that Fyn regulates muscle mass by suppressing autophagy through Fyn-STAT3-VPS34 signaling pathway. More...

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Detalles Bibliográficos
Autores principales: Uehara, Ryota, Yamada, Eijiro, Uehara, Masaya, Nakajima, Yasuyo, Horiguchi, Kazuhiko, Ishida, Emi, Matsumoto, Shunichi, Okada, Shuichi, Yamada, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089854/
http://dx.doi.org/10.1210/jendso/bvab048.904