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DHT Causes Liver Steatosis via Transcriptional Regulation of SCAP in Lean female Mice

Hyperandrogenemia (HA) and insulin resistance are hallmarks of polycystic ovary syndrome (PCOS). These hallmarks are also integral elements of non-alcoholic fatty liver disease (NALFD). Administering low dose dihydrotestosterone (DHT) induced a lean PCOS-like female mouse model. The molecular mechan...

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Detalles Bibliográficos
Autores principales: Andrisse, Stanley, Myer, Jessie, Bogle, Dilip “Bobby”, Eregha, Nicole, Lofton, Taylor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089858/
http://dx.doi.org/10.1210/jendso/bvab048.1642