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Volanesorsen, an Antisense Oligonucleotide to Apolipoprotein-CIII, Decreases Triglycerides and Increases Lipoprotein Lipase Activity in Partial Lipodystrophy

Partial lipodystrophy syndromes (PL) involve selective deficiency of adipose tissue, with regional deficiency of fat in the lower extremities and preservation or even excess fat in the face and neck. Clinical features typical of PL include severe insulin resistance, diabetes mellitus, hypertriglycer...

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Detalles Bibliográficos
Autores principales: Lightbourne, Marissa, Brite, Brianna, Startzell, Megan S, Kimberley, Bruce, Eckel, Robert, Brown, Rebecca J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089895/
http://dx.doi.org/10.1210/jendso/bvab048.621