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Causal Effect of Fibroblast Growth Factor 23 on Osteoporosis and Cardiometabolic Disorders: A Mendelian Randomization Study

Pathological excess of fibroblast growth factor 23 (FGF23) causes mineral and bone disorders. However, the causality of FGF23 in the development of osteoporosis remains unknown. Whether FGF23 has systemic effects on cardio-metabolic disorders beyond regulating mineral metabolism is also controversia...

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Detalles Bibliográficos
Autores principales: Yokomoto-Umakoshi, Maki, Umakoshi, Hironobu, Miyazawa, Takashi, Ogata, Masatoshi, Sakamoto, Ryuichi, Ogawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089954/
http://dx.doi.org/10.1210/jendso/bvab048.552