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Sustained Morphine Delivery Suppresses Bone Formation and Alters Metabolic and Circulating miRNA Profiles in Mice

Opioid use is associated with a three to four-fold increase in fracture risk, which is higher in males compared to females. Although one component of that risk may be falls, there is also evidence of altered bone remodeling. However, the mechanisms of these effects are not entirely clear. Our aim wa...

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Detalles Bibliográficos
Autores principales: Carvalho, Adriana Lelis, Brooks, Daniel J, Barlow, Deborah, Houseknecht, Karen, Bouxsein, Mary, Lian, Jane B, King, Tamara, Farina, Nicholas H, Motyl, Katherine J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090320/
http://dx.doi.org/10.1210/jendso/bvab048.487