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P53 Gain-of-Function Mutants and Steroids in Ovarian Cancer Cell Metastasis

High-grade serous ovarian cancer (HGSOC) is a heterogeneous disease for which there currentlyis no cure. Because p53 is mutated in >90% of all ovarian cancer, we studied specific gain-of-function (GOF) p53 mutants and steroid hormones for tumor morphology and metastasis in vivo. For this, we anal...

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Detalles Bibliográficos
Autores principales: Candelaria, Nicholes, Padmanabhan, Achuth, Lanz, Rainer, Wong, Kwong, Richards, JoAnne S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090435/
http://dx.doi.org/10.1210/jendso/bvab048.1567