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Vitamin D Deficiency Induces Macrophage Pro-Inflammatory Phenotype via ER Stress-Mediated Activation of Renin-Angiotensin System

Chronic inflammation and local activation of the renin-angiotensin-aldosterone system (RAAS) play a pivotal role in the pathogenesis and progression of diabetic complications. In patients with type 2 diabetes (T2DM), the prevalence of vitamin D deficiency is almost twice that of non-diabetics, and v...

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Detalles Bibliográficos
Autores principales: Bauerle, Kevin Thomas, Oh, Jisu, Riek, Amy Elizabeth, Dusso, Adriana, Castro-Grattoni, Anabel L, Gomez, R Ariel, Sequeira-Lopez, Maria L, Bernal-Mizrachi, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090451/
http://dx.doi.org/10.1210/jendso/bvab048.620