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Calcineurin-NFATc4 Pathway Is Activated Upon K(+)-stimulation of Adrenal Aldosterone Production

The mineralocorticoid aldosterone secreted by the adrenal zona glomerulosa (ZG) cells promote renal K(+) secretion and Na(+) reabsorption; thereby it is critical for the control of ion homeostasis and blood pressure. While the Ca(2+)/calmodulin-dependent protein kinase (CAMK) pathway regulating K(+)...

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Detalles Bibliográficos
Autores principales: Berber, Mesut, Leng, Sining, Beuschlein, Felix, Breault, David T, Loffing, Johannes, Ribas, David Penton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090507/
http://dx.doi.org/10.1210/jendso/bvab048.1638