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New Transcriptional Insights into Silent and Active Corticotroph Pituitary Tumors at Single Cell Resolution

Silent pituitary corticotroph tumors derive from the Tpit (aka TBX19) pituitary lineage. Accounting for ~ 30% of corticotroph tumors, they are not infrequently clinically aggressive and invade locally into adjacent sellar structures, making complete surgical resection challenging and contributing to...

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Detalles Bibliográficos
Autores principales: Zhang, Dongyun, Hugo, Willy, Bergsneider, Marvin, Wang, Marilene B, Kim, Won, Vinters, Harry, Heaney, Anthony P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090559/
http://dx.doi.org/10.1210/jendso/bvab048.1318