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Canine Pituitary Organoids as 3D In Vitro Model for Cushing Disease

Cushing disease (CD) is a serious endocrine disorder that is most often caused by an ACTH-secreting pituitary adenoma. Patients can be treated medically when surgery is not an option or was unsuccessful. However, currently used pituitary-targeting drugs are effective in only 40% of patients. To effi...

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Detalles Bibliográficos
Autores principales: Sanders, Karin, Ringnalda, Femke C A, van de Wetering, Marc L, Kooistra, Hans S, Meij, Björn P, Clevers, Hans, Galac, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090587/
http://dx.doi.org/10.1210/jendso/bvab048.1085