Cargando…

Canine Pituitary Organoids as 3D In Vitro Model for Cushing Disease

Cushing disease (CD) is a serious endocrine disorder that is most often caused by an ACTH-secreting pituitary adenoma. Patients can be treated medically when surgery is not an option or was unsuccessful. However, currently used pituitary-targeting drugs are effective in only 40% of patients. To effi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sanders, Karin, Ringnalda, Femke C A, van de Wetering, Marc L, Kooistra, Hans S, Meij, Björn P, Clevers, Hans, Galac, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Neuroendocrinology and Pituitary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090587/ http://dx.doi.org/10.1210/jendso/bvab048.1085

Ejemplares similares

OR20-05 Generation Of CDH23-mutated Pituitary Neuroendocrine Tumor Organoids From Induced Pluripotent Stem Cells To Model Cushing’s Disease Pathogenesis
por: Chakrabarti, Jayati, et al.
Publicado: (2023)

SAT-300 Evading Death: Noxa in Cushing’s Disease Pituitary Adenomas
por: Alvarez, Reinier, et al.
Publicado: (2020)

SAT-248 Cushing’s Disease with Two ACTH-Producing Pituitary Tumors
por: Mathai, Christine, et al.
Publicado: (2020)

THU009 Subclinical Cushing’s Syndrome In An ACTH-secreting Pituitary Macroadenoma
por: Akabogu, Nwamaka Gloria, et al.
Publicado: (2023)

MON-405 Cushing's Disease: An Oligosymptomatic Patient with ACTH-Secreting Pituitary Macroadenoma
por: Manrique Franco, Katty, et al.
Publicado: (2019)

Melanocortin 2 Receptor Antagonists in Canine Cushing’s Disease: In Vitro Studies
por: Sanders, Karin, et al.
Publicado: (2021)

SAT-304 Pituitary Stem Cells May Drive Adenomas Causing Cushing’s Disease
por: Asuzu, David, et al.
Publicado: (2020)

Novel Pituitary Organoid Model as Powerful Tool to Unravel Pituitary Stem Cell Biology Across Ages and Disease
por: J Vankelecom, Hugo E, et al.
Publicado: (2021)

Management of Persistent Cushing’s Disease Despite Prior Pituitary Adenoma Resection in a Pregnant Patient
por: Leiter, Amanda, et al.
Publicado: (2021)

THU108 Pituitary Carcinoma Diagnosed After Ten Years Of Smoldering Ectopic Nasopharyngeal Cushing’s
por: Carafone, Lindsay, et al.
Publicado: (2023)

SAT-459 Hypothalamic-Pituitary-Gonadal (HPG) and Hypothalamic-Pituitary-Thyroid (HPT) Axes in Cushing Syndrome (CS): A Retrospective Cohort Study
por: Shekhar, Skand, et al.
Publicado: (2019)

MON-408 Development of Rapidly Progressive Cushing's Disease Following Pituitary Apoplexy Several Years Prior
por: Ortegon Zambrano, Pilar, et al.
Publicado: (2019)

Desmopressin Test in Silent Corticothoph Pituitary Adenomas, a Preliminary Study - a Comparison With Cushing Disease
por: Huayllas, Martha Katherine, et al.
Publicado: (2021)

THU011 Cushing’s Disease Diagnosis Challenge With Standard Pituitary MRI: A Clinical Case Report
por: Kasiri, Elnaz, et al.
Publicado: (2023)

Melanocortin 2 receptor antagonists in canine pituitary-dependent hypercortisolism: in vitro studies
por: Sanders, Karin, et al.
Publicado: (2018)

SUN-463 Tumor Shrinkage with Preoperative Relacorilant Therapy in Two Patients with Cushing Disease Due to Pituitary Macroadenomas
por: Terzolo, Massimo, et al.
Publicado: (2019)

SAT-259 Acromegaly by Pituitary Adenoma Associated with ACTH-Independent Cushing Syndrome by Adrenal Carcinoma: Case Report
por: Minuzzi, Ricardo Kunde, et al.
Publicado: (2020)

MON-407 Tumor Control after Radiotherapy and Temozolomide in a Cushing's Disease Patient with Giant Aggressive Pituitary Tumor
por: Valente do Couto, Hugo, et al.
Publicado: (2019)

MON-295 Desmopressin Test in Silent Corticothoph Pituitary Adenomas, a Preliminary Study - a Comparison with Cushing Disease
por: Huayllas, Martha Katherine, et al.
Publicado: (2020)

Cushing’s Disease (CD) Due to ACTH-Secreting Pituitary Microadenoma Incidentally Discovered on a Sestamibi Scan for Primary Hyperparathyroidism
por: Mehmood, Hassan, et al.
Publicado: (2021)

THU036 (68)Ga-DOTATOC PET/CT In Localization Of ACTH-producing Pituitary Tumors In Patients With Cushing Disease
por: Kim, Kyungwon
Publicado: (2023)

THU010 A Case Of Cushing(')s Disease Due To T-pit Positive, ACTH Negative Aggressive Corticotroph Pituitary Adenoma
por: Gopinath, Chaitra, et al.
Publicado: (2023)

THU012 Incidental Pituitary Adenoma In A Patient With Ectopic ACTH Secreting Cushing Syndrome - A Diagnostic Conundrum
por: Nali, Meenakshi Sinduri, et al.
Publicado: (2023)

MON-469 Pituitary Corticotroph Lesions: Clinical, Biochemical, and Pathological Characterization of Cushing Disease, Silent Corticotroph Adenomas, and Corticotroph Hyperplasia
por: Castlen, Joseph, et al.
Publicado: (2019)

LBMON176 Management, Safety, And Efficacy Of Osilodrostat Treatment In US Patients With Non-pituitary Cushing's Syndrome: Results From The ILLUSTRATE Study
por: Auchus, Richard Joseph, et al.
Publicado: (2022)

SAT-256 The Ever Confusing Cushing’s Work Up: Is It Real? Is It Pseudo Cushing’s’? Or Could It Be Factitious
por: Ghalib, Luma, et al.
Publicado: (2020)

Hypercoagulability in ACTH-Dependent Cushing Syndrome
por: Singh Sumal, Amit Kartar, et al.
Publicado: (2021)

Occult Carcinoid Causes Cushing’s Syndrome
por: Meftali, Sabrina, et al.
Publicado: (2021)

FRI371 Serum Androstenedione As An Additive Biomarker In Ectopic Cushing’s Syndrome Evaluation
por: Zhang, Sherry, et al.
Publicado: (2023)

THU021 Mysterious Resolution Of Cushing’s Disease
por: Whiteman, Daniel R, et al.
Publicado: (2023)

THU040 Different Patient Versus Provider Perspectives On Living With Cushing’s Disease
por: Halstrom, Amanda, et al.
Publicado: (2023)

RF01 | PMON168 Hedgehog-Induced Somatostatin Receptor Expression is Inhibited by the Activation of the Glucocorticoid Receptor Signaling Pathway in Human Pituitary Adenoma Organoids
por: Zavros, Yana, et al.
Publicado: (2022)

OR06-01 The Role of Germline Defects in Cushing’s Disease
por: Hernández-Ramírez, Laura C, et al.
Publicado: (2020)

SAT-277 A Fierce Presentation of Cushing Disease
por: Al Sabie, Farah Laith, et al.
Publicado: (2020)

Antisense Oligonucleotides as a Novel Therapy for Cushing’s Disease
por: Eltumi, Hanan, et al.
Publicado: (2021)

MON-466 Transcriptome Dynamics of in vitro Human Pituitary Tumor Primary Culture
por: Zhang, Dongyun, et al.
Publicado: (2019)

SAT-LB46 Depression as an Atypical Presentation of Cushing’s Disease
por: Pahwa, Dhivya, et al.
Publicado: (2020)

MON-328 Disorders of Glucose Metabolism in Cushing Syndrome in Uzbekistan
por: Narimova, Gulchekhra Djumaniyazovna, et al.
Publicado: (2020)

USP8 Somatic Mutations in Cushing’s Disease and Silent Corticotropinomas
por: Lamback, Elisa Baranski, et al.
Publicado: (2021)

Long-Term Corticotroph Function Following Cure of Cushing’s Syndrome
por: Schernthaner-Reiter, Marie Helene, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_trf0v06prc8o1h1vcgpaoeamrp