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MIF Inhibition Suppresses Cell Viability and Induces Apoptosis via the ATF4-CHOP Pathway in Mouse Pituitary AtT-20 Cells

Cushing’s disease (CD) is characterized by cortisol overproduction due to ACTH hypersecretion from a pituitary tumour (PT). With an incidence of approximately 1.2 to 2.4 cases per million per year, CD patients have higher rates of morbidity and mortality than the general population. Surgical managem...

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Detalles Bibliográficos
Autores principales: Wang, Jason, Satou, Motoyasu, Tateno, Tae, Willette, Sarah, Yang, Rui Zhe, Kitayoshi, Fumika, Teramachi, Mariko, Sugimoto, Hiroyuki, Chik, Constance L, Tateno, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090611/
http://dx.doi.org/10.1210/jendso/bvab048.1108