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MIF Inhibition Suppresses Cell Viability and Induces Apoptosis via the ATF4-CHOP Pathway in Mouse Pituitary AtT-20 Cells
Cushing’s disease (CD) is characterized by cortisol overproduction due to ACTH hypersecretion from a pituitary tumour (PT). With an incidence of approximately 1.2 to 2.4 cases per million per year, CD patients have higher rates of morbidity and mortality than the general population. Surgical managem...
Autores principales: | Wang, Jason, Satou, Motoyasu, Tateno, Tae, Willette, Sarah, Yang, Rui Zhe, Kitayoshi, Fumika, Teramachi, Mariko, Sugimoto, Hiroyuki, Chik, Constance L, Tateno, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090611/ http://dx.doi.org/10.1210/jendso/bvab048.1108 |
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