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Antisense Oligonucleotides as a Novel Therapy for Cushing’s Disease

Background: Cushing’s disease (CD) is caused by high levels of blood cortisol resulting from excess secretion of ACTH from a corticotroph adenoma in the anterior pituitary gland. Clinical features include hypertension, diabetes, osteoporosis, and depression. If untreated CD has an increased mortalit...

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Detalles Bibliográficos
Autores principales: Eltumi, Hanan, Whatmore, Jacob, Kemp, Elizabeth Helen, Newell-Price, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090621/
http://dx.doi.org/10.1210/jendso/bvab048.1084