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Circulating LEAP-2 Levels in Adult Growth Hormone Deficiency and Their Relationship With IGF-1

Liver enriched antimicrobial peptide-2 (LEAP-2) is an endogenous antagonist of ghrelin, which acts as an allosteric modulator of growth hormone secretagogue receptors. It is expressed predominantly in liver, followed by kidney, jejunum, duodenum and stomach. Its expression in conditions of metabolic...

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Detalles Bibliográficos
Autores principales: Vergani, Edoardo, Bruno, Carmine, Gavotti, Cesare, Capobianco, Emmanuel, Currò, Diego, Mancini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090666/
http://dx.doi.org/10.1210/jendso/bvab048.1088