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PFOA Exposure Prior to Hepatocyte Differentiation Leads to Gene Expression Changes Implicated in Non-Alcoholic Fatty Liver Disease

Background: Perfluorooctanoic acid (PFOA), is a persistent fluorinated compound with oil and water repelling properties found in cookware, food packaging and municipal water systems. Adult animals exposed to PFOA develop hepatomegaly, fatty liver, peroxisome proliferation, and immunotoxicity. Rodent...

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Detalles Bibliográficos
Autores principales: Hanke, Stephanie, Joshi, Apoorva, Fu, Weixuan, Wang, Paul, Tarapore, Pheruza, Simmons, Rebecca Anne, Pinney, Sara Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090679/
http://dx.doi.org/10.1210/jendso/bvab048.1003