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PFOA Exposure Prior to Hepatocyte Differentiation Leads to Gene Expression Changes Implicated in Non-Alcoholic Fatty Liver Disease
Background: Perfluorooctanoic acid (PFOA), is a persistent fluorinated compound with oil and water repelling properties found in cookware, food packaging and municipal water systems. Adult animals exposed to PFOA develop hepatomegaly, fatty liver, peroxisome proliferation, and immunotoxicity. Rodent...
Autores principales: | Hanke, Stephanie, Joshi, Apoorva, Fu, Weixuan, Wang, Paul, Tarapore, Pheruza, Simmons, Rebecca Anne, Pinney, Sara Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090679/ http://dx.doi.org/10.1210/jendso/bvab048.1003 |
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