PECAM‐1 supports leukocyte diapedesis by tension‐dependent dephosphorylation of VE‐cadherin

Leukocyte extravasation is an essential step during the immune response and requires the destabilization of endothelial junctions. We have shown previously that this process depends in vivo on the dephosphorylation of VE‐cadherin‐Y731. Here, we reveal the underlying mechanism. Leukocyte‐induced stim...

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Detalles Bibliográficos
Autores principales: Arif, Nida, Zinnhardt, Maren, Nyamay’Antu, Alengo, Teber, Denise, Brückner, Randy, Schaefer, Kerstin, Li, Yu‐Tung, Trappmann, Britta, Grashoff, Carsten, Vestweber, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090850/
https://www.ncbi.nlm.nih.gov/pubmed/33604918
http://dx.doi.org/10.15252/embj.2020106113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090850/
https://www.ncbi.nlm.nih.gov/pubmed/33604918
http://dx.doi.org/10.15252/embj.2020106113

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